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Icariin Activates Autophagy via Down-Regulation of the NF-κB Signaling-Mediated Apoptosis in Chondrocytes
Osteoarthritis (OA) is a common chronic and degenerative joint condition that is mainly characterized by cartilage degradation, osteophyte formation, and joint stiffness. The NF-κB signaling pathway in inflammation, autophagy, and apoptosis plays a prominent role in the progression of OA. Icariin, a...
Autores principales: | Mi, Bobin, Wang, Junqing, Liu, Yi, Liu, Jing, Hu, Liangcong, Panayi, Adriana C., Liu, Guohui, Zhou, Wu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008570/ https://www.ncbi.nlm.nih.gov/pubmed/29950992 http://dx.doi.org/10.3389/fphar.2018.00605 |
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