Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis

A patient with congenital insensitivity to pain with anhidrosis (CIPA) underwent revision of total hip arthroplasty under general anesthesia with only propofol. During surgery, neither elevation of stress hormones nor hemodynamic changes associated with pain occurred; however, when blood was rapidly...

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Autores principales: Sugiyama, Yuki, Gotoh, Sayako, Urasawa, Masatoshi, Kawamata, Mikito, Nakajima, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008617/
https://www.ncbi.nlm.nih.gov/pubmed/29971168
http://dx.doi.org/10.1155/2018/9593458
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author Sugiyama, Yuki
Gotoh, Sayako
Urasawa, Masatoshi
Kawamata, Mikito
Nakajima, Koichi
author_facet Sugiyama, Yuki
Gotoh, Sayako
Urasawa, Masatoshi
Kawamata, Mikito
Nakajima, Koichi
author_sort Sugiyama, Yuki
collection PubMed
description A patient with congenital insensitivity to pain with anhidrosis (CIPA) underwent revision of total hip arthroplasty under general anesthesia with only propofol. During surgery, neither elevation of stress hormones nor hemodynamic changes associated with pain occurred; however, when blood was rapidly lost, compensatory tachycardia was observed. Although patients with CIPA are complicated with autonomic disturbance due to dysfunction of postganglionic sympathetic fibers, this compensatory response indicated that the adrenal glands in patients with CIPA secrete catecholamine as part of a compensatory response during bleeding under general anesthesia.
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spelling pubmed-60086172018-07-03 Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis Sugiyama, Yuki Gotoh, Sayako Urasawa, Masatoshi Kawamata, Mikito Nakajima, Koichi Case Rep Anesthesiol Case Report A patient with congenital insensitivity to pain with anhidrosis (CIPA) underwent revision of total hip arthroplasty under general anesthesia with only propofol. During surgery, neither elevation of stress hormones nor hemodynamic changes associated with pain occurred; however, when blood was rapidly lost, compensatory tachycardia was observed. Although patients with CIPA are complicated with autonomic disturbance due to dysfunction of postganglionic sympathetic fibers, this compensatory response indicated that the adrenal glands in patients with CIPA secrete catecholamine as part of a compensatory response during bleeding under general anesthesia. Hindawi 2018-06-03 /pmc/articles/PMC6008617/ /pubmed/29971168 http://dx.doi.org/10.1155/2018/9593458 Text en Copyright © 2018 Yuki Sugiyama et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sugiyama, Yuki
Gotoh, Sayako
Urasawa, Masatoshi
Kawamata, Mikito
Nakajima, Koichi
Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
title Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
title_full Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
title_fullStr Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
title_full_unstemmed Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
title_short Hemodynamic Response to Massive Bleeding in a Patient with Congenital Insensitivity to Pain with Anhidrosis
title_sort hemodynamic response to massive bleeding in a patient with congenital insensitivity to pain with anhidrosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008617/
https://www.ncbi.nlm.nih.gov/pubmed/29971168
http://dx.doi.org/10.1155/2018/9593458
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