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Deep Transcranial Magnetic Stimulation: Improved Coil Design and Assessment of the Induced Fields Using MIDA Model

Stimulation of deep brain structures by transcranial magnetic stimulation (TMS) is a method for activating deep neurons in the brain and can be beneficial for the treatment of psychiatric and neurological disorders. To numerically investigate the possibility for deeper brain stimulation (electric fi...

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Detalles Bibliográficos
Autores principales: Samoudi, Amine M., Tanghe, Emmeric, Martens, Luc, Joseph, Wout
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008619/
https://www.ncbi.nlm.nih.gov/pubmed/29967781
http://dx.doi.org/10.1155/2018/7061420
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author Samoudi, Amine M.
Tanghe, Emmeric
Martens, Luc
Joseph, Wout
author_facet Samoudi, Amine M.
Tanghe, Emmeric
Martens, Luc
Joseph, Wout
author_sort Samoudi, Amine M.
collection PubMed
description Stimulation of deep brain structures by transcranial magnetic stimulation (TMS) is a method for activating deep neurons in the brain and can be beneficial for the treatment of psychiatric and neurological disorders. To numerically investigate the possibility for deeper brain stimulation (electric fields reaching the hippocampus, the nucleus accumbens, and the cerebellum), combined TMS coils using the double-cone coil with the Halo coil (HDA) were modeled and investigated. Numerical simulations were performed using MIDA: a new multimodal imaging-based detailed anatomical model of the human head and neck. The 3D distributions of magnetic flux density and electric field were calculated. The percentage of volume of each tissue that is exposed to electric field amplitude equal or greater than 50% of the maximum amplitude of E in the cortex for each coil was calculated to quantify the electric field spread (V50). Results show that only the HDA coil can spread electric fields to the hippocampus, the nucleus accumbens, and the cerebellum with V50 equal to 0.04%, 1.21%, and 6.2%, respectively.
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spelling pubmed-60086192018-07-02 Deep Transcranial Magnetic Stimulation: Improved Coil Design and Assessment of the Induced Fields Using MIDA Model Samoudi, Amine M. Tanghe, Emmeric Martens, Luc Joseph, Wout Biomed Res Int Research Article Stimulation of deep brain structures by transcranial magnetic stimulation (TMS) is a method for activating deep neurons in the brain and can be beneficial for the treatment of psychiatric and neurological disorders. To numerically investigate the possibility for deeper brain stimulation (electric fields reaching the hippocampus, the nucleus accumbens, and the cerebellum), combined TMS coils using the double-cone coil with the Halo coil (HDA) were modeled and investigated. Numerical simulations were performed using MIDA: a new multimodal imaging-based detailed anatomical model of the human head and neck. The 3D distributions of magnetic flux density and electric field were calculated. The percentage of volume of each tissue that is exposed to electric field amplitude equal or greater than 50% of the maximum amplitude of E in the cortex for each coil was calculated to quantify the electric field spread (V50). Results show that only the HDA coil can spread electric fields to the hippocampus, the nucleus accumbens, and the cerebellum with V50 equal to 0.04%, 1.21%, and 6.2%, respectively. Hindawi 2018-06-05 /pmc/articles/PMC6008619/ /pubmed/29967781 http://dx.doi.org/10.1155/2018/7061420 Text en Copyright © 2018 Amine M. Samoudi et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Samoudi, Amine M.
Tanghe, Emmeric
Martens, Luc
Joseph, Wout
Deep Transcranial Magnetic Stimulation: Improved Coil Design and Assessment of the Induced Fields Using MIDA Model
title Deep Transcranial Magnetic Stimulation: Improved Coil Design and Assessment of the Induced Fields Using MIDA Model
title_full Deep Transcranial Magnetic Stimulation: Improved Coil Design and Assessment of the Induced Fields Using MIDA Model
title_fullStr Deep Transcranial Magnetic Stimulation: Improved Coil Design and Assessment of the Induced Fields Using MIDA Model
title_full_unstemmed Deep Transcranial Magnetic Stimulation: Improved Coil Design and Assessment of the Induced Fields Using MIDA Model
title_short Deep Transcranial Magnetic Stimulation: Improved Coil Design and Assessment of the Induced Fields Using MIDA Model
title_sort deep transcranial magnetic stimulation: improved coil design and assessment of the induced fields using mida model
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008619/
https://www.ncbi.nlm.nih.gov/pubmed/29967781
http://dx.doi.org/10.1155/2018/7061420
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