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In Vitro and Ex Vivo Chemopreventive Action of Mauritia flexuosa Products
Mauritia flexuosa (Arecaceae), known as “Buriti,” is a Brazilian palm tree with high economic potential for local communities. Herein, we investigated the phytochemistry profile and antioxidant potential of M. flexuosa fruits and determined the bioaccessibility of phenolic compounds. Peels revealed...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008795/ https://www.ncbi.nlm.nih.gov/pubmed/29967646 http://dx.doi.org/10.1155/2018/2051279 |
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author | Pereira-Freire, Joilane Alves Oliveira, George Laylson da Silva Lima, Layana Karine Farias Ramos, Carla Lorena Silva Arcanjo-Medeiros, Stella Regina de Lima, Ana Cristina Silva Teixeira, Sabrina Almondes de Oliveira, Guilherme Antônio Lopes Nunes, Nárcia Mariana Fonseca Amorim, Vivianne Rodrigues Lopes, Luciano da Silva Rolim, Larissa Araújo da Costa-Júnior, Joaquim Soares Ferreira, Paulo Michel Pinheiro |
author_facet | Pereira-Freire, Joilane Alves Oliveira, George Laylson da Silva Lima, Layana Karine Farias Ramos, Carla Lorena Silva Arcanjo-Medeiros, Stella Regina de Lima, Ana Cristina Silva Teixeira, Sabrina Almondes de Oliveira, Guilherme Antônio Lopes Nunes, Nárcia Mariana Fonseca Amorim, Vivianne Rodrigues Lopes, Luciano da Silva Rolim, Larissa Araújo da Costa-Júnior, Joaquim Soares Ferreira, Paulo Michel Pinheiro |
author_sort | Pereira-Freire, Joilane Alves |
collection | PubMed |
description | Mauritia flexuosa (Arecaceae), known as “Buriti,” is a Brazilian palm tree with high economic potential for local communities. Herein, we investigated the phytochemistry profile and antioxidant potential of M. flexuosa fruits and determined the bioaccessibility of phenolic compounds. Peels revealed upper values for phenols, flavonoids, carotenoids, tannins, and ascorbic acid when compared to the pulps and endocarps. All samples showed capacity to scavenger free radicals (0.5, 1.0, 2.0, 4.0, and 8.0 mg/mL) but peels presented higher scavenger action in all methods explored. Phenolic compounds identified by HPLC displayed reduced bioaccessibility after in vitro simulated gastrointestinal digestion for pulp (38.7%), peel (18.7%), and endocarp (22.3%) extracts (P < 0.05). Buriti fruits also protected rat blood cells against lysis induced by peroxyl radicals. We demonstrated the promising chemopreventive potentialities of M. flexuosa fruits and their by-products and peels with higher quantities of bioactive compounds and phenolic substances before and after in vitro bioaccessibility investigation. In Brazil, these parts are discarded or underused, mainly as feed for ruminant animals. Consequently, it is extremely important to explore nutritional characteristics of these by-products for human/livestock foods and to install biofriendly techniques and sustainable biotechnology handling of natural resources. |
format | Online Article Text |
id | pubmed-6008795 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-60087952018-07-02 In Vitro and Ex Vivo Chemopreventive Action of Mauritia flexuosa Products Pereira-Freire, Joilane Alves Oliveira, George Laylson da Silva Lima, Layana Karine Farias Ramos, Carla Lorena Silva Arcanjo-Medeiros, Stella Regina de Lima, Ana Cristina Silva Teixeira, Sabrina Almondes de Oliveira, Guilherme Antônio Lopes Nunes, Nárcia Mariana Fonseca Amorim, Vivianne Rodrigues Lopes, Luciano da Silva Rolim, Larissa Araújo da Costa-Júnior, Joaquim Soares Ferreira, Paulo Michel Pinheiro Evid Based Complement Alternat Med Research Article Mauritia flexuosa (Arecaceae), known as “Buriti,” is a Brazilian palm tree with high economic potential for local communities. Herein, we investigated the phytochemistry profile and antioxidant potential of M. flexuosa fruits and determined the bioaccessibility of phenolic compounds. Peels revealed upper values for phenols, flavonoids, carotenoids, tannins, and ascorbic acid when compared to the pulps and endocarps. All samples showed capacity to scavenger free radicals (0.5, 1.0, 2.0, 4.0, and 8.0 mg/mL) but peels presented higher scavenger action in all methods explored. Phenolic compounds identified by HPLC displayed reduced bioaccessibility after in vitro simulated gastrointestinal digestion for pulp (38.7%), peel (18.7%), and endocarp (22.3%) extracts (P < 0.05). Buriti fruits also protected rat blood cells against lysis induced by peroxyl radicals. We demonstrated the promising chemopreventive potentialities of M. flexuosa fruits and their by-products and peels with higher quantities of bioactive compounds and phenolic substances before and after in vitro bioaccessibility investigation. In Brazil, these parts are discarded or underused, mainly as feed for ruminant animals. Consequently, it is extremely important to explore nutritional characteristics of these by-products for human/livestock foods and to install biofriendly techniques and sustainable biotechnology handling of natural resources. Hindawi 2018-06-03 /pmc/articles/PMC6008795/ /pubmed/29967646 http://dx.doi.org/10.1155/2018/2051279 Text en Copyright © 2018 Joilane Alves Pereira-Freire et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Pereira-Freire, Joilane Alves Oliveira, George Laylson da Silva Lima, Layana Karine Farias Ramos, Carla Lorena Silva Arcanjo-Medeiros, Stella Regina de Lima, Ana Cristina Silva Teixeira, Sabrina Almondes de Oliveira, Guilherme Antônio Lopes Nunes, Nárcia Mariana Fonseca Amorim, Vivianne Rodrigues Lopes, Luciano da Silva Rolim, Larissa Araújo da Costa-Júnior, Joaquim Soares Ferreira, Paulo Michel Pinheiro In Vitro and Ex Vivo Chemopreventive Action of Mauritia flexuosa Products |
title |
In Vitro and Ex Vivo Chemopreventive Action of Mauritia flexuosa Products |
title_full |
In Vitro and Ex Vivo Chemopreventive Action of Mauritia flexuosa Products |
title_fullStr |
In Vitro and Ex Vivo Chemopreventive Action of Mauritia flexuosa Products |
title_full_unstemmed |
In Vitro and Ex Vivo Chemopreventive Action of Mauritia flexuosa Products |
title_short |
In Vitro and Ex Vivo Chemopreventive Action of Mauritia flexuosa Products |
title_sort | in vitro and ex vivo chemopreventive action of mauritia flexuosa products |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008795/ https://www.ncbi.nlm.nih.gov/pubmed/29967646 http://dx.doi.org/10.1155/2018/2051279 |
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