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Role of Lipotoxicity and Contribution of the Renin-Angiotensin System in the Development of Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is a common and significant condition associated with hyperandrogenism, infertility, low quality of life, and metabolic comorbidities. One possible explanation of PCOS development is cellular dysfunction induced by nonesterified fatty acids (NEFAs), that is, lipotoxi...

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Detalles Bibliográficos
Autores principales: Connolly, Alexandre, Leblanc, Samuel, Baillargeon, Jean-Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008888/
https://www.ncbi.nlm.nih.gov/pubmed/29971102
http://dx.doi.org/10.1155/2018/4315413