Enhanced susceptibility of cancer cells to oncolytic rhabdo-virotherapy by expression of Nodamura virus protein B2 as a suppressor of RNA interference

Antiviral responses are barriers that must be overcome for efficacy of oncolytic virotherapy. In mammalian cells, antiviral responses involve the interferon pathway, a protein-signaling cascade that alerts the immune system and limits virus propagation. Tumour-specific defects in interferon signalin...

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Detalles Bibliográficos
Autores principales: Bastin, Donald, Aitken, Amelia S., Pelin, Adrian, Pikor, Larissa A., Crupi, Mathieu J. F., Huh, Michael S., Bourgeois-Daigneault, Marie-Claude, Bell, John C., Ilkow, Carolina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008949/
https://www.ncbi.nlm.nih.gov/pubmed/29921327
http://dx.doi.org/10.1186/s40425-018-0366-2

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