The Rationale for Monitoring Cognitive Function in Multiple Sclerosis: Practical Issues for Clinicians

About half of patients with multiple sclerosis exhibit cognitive impairment which negatively affects their quality of life. The assessment of cognitive function in routine clinical practice is still undervalued, although various tools have been proposed for this reason. In this article, we describe...

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Autores principales: Bakirtzis, Christos, Ioannidis, Panagiotis, Messinis, Lambros, Nasios, Grigorios, Konstantinopoulou, Elina, Papathanasopoulos, Panagiotis, Grigoriadis, Nikolaos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2018
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008981/
https://www.ncbi.nlm.nih.gov/pubmed/30008964
http://dx.doi.org/10.2174/1874205X01812010031
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author Bakirtzis, Christos
Ioannidis, Panagiotis
Messinis, Lambros
Nasios, Grigorios
Konstantinopoulou, Elina
Papathanasopoulos, Panagiotis
Grigoriadis, Nikolaos
author_facet Bakirtzis, Christos
Ioannidis, Panagiotis
Messinis, Lambros
Nasios, Grigorios
Konstantinopoulou, Elina
Papathanasopoulos, Panagiotis
Grigoriadis, Nikolaos
author_sort Bakirtzis, Christos
collection PubMed
description About half of patients with multiple sclerosis exhibit cognitive impairment which negatively affects their quality of life. The assessment of cognitive function in routine clinical practice is still undervalued, although various tools have been proposed for this reason. In this article, we describe the potential benefits of implementing cognitive assessment tools in routine follow -ups of MS patients. Early detection of changes in cognitive performance may provide evidence of disease activity, could unmask depression or medication side-effects and provide suitable candidates for cognitive rehabilitation. Since apathy and cognitive deficiencies are common presenting symptoms in Progressive Multifocal Leukoencephalopathy, we discuss the utility of frequent monitoring of mental status in multiple sclerosis patients at increased risk. In addition, we propose a relevant algorithm aiming to incorporate a systematic evaluation of cognitive function in every day clinical practice in multiple sclerosis.
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spelling pubmed-60089812018-07-13 The Rationale for Monitoring Cognitive Function in Multiple Sclerosis: Practical Issues for Clinicians Bakirtzis, Christos Ioannidis, Panagiotis Messinis, Lambros Nasios, Grigorios Konstantinopoulou, Elina Papathanasopoulos, Panagiotis Grigoriadis, Nikolaos Open Neurol J Neurology About half of patients with multiple sclerosis exhibit cognitive impairment which negatively affects their quality of life. The assessment of cognitive function in routine clinical practice is still undervalued, although various tools have been proposed for this reason. In this article, we describe the potential benefits of implementing cognitive assessment tools in routine follow -ups of MS patients. Early detection of changes in cognitive performance may provide evidence of disease activity, could unmask depression or medication side-effects and provide suitable candidates for cognitive rehabilitation. Since apathy and cognitive deficiencies are common presenting symptoms in Progressive Multifocal Leukoencephalopathy, we discuss the utility of frequent monitoring of mental status in multiple sclerosis patients at increased risk. In addition, we propose a relevant algorithm aiming to incorporate a systematic evaluation of cognitive function in every day clinical practice in multiple sclerosis. Bentham Open 2018-05-31 /pmc/articles/PMC6008981/ /pubmed/30008964 http://dx.doi.org/10.2174/1874205X01812010031 Text en © 2018 Bakirtzis et al. https://creativecommons.org/licenses/by/4.0/legalcode This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Bakirtzis, Christos
Ioannidis, Panagiotis
Messinis, Lambros
Nasios, Grigorios
Konstantinopoulou, Elina
Papathanasopoulos, Panagiotis
Grigoriadis, Nikolaos
The Rationale for Monitoring Cognitive Function in Multiple Sclerosis: Practical Issues for Clinicians
title The Rationale for Monitoring Cognitive Function in Multiple Sclerosis: Practical Issues for Clinicians
title_full The Rationale for Monitoring Cognitive Function in Multiple Sclerosis: Practical Issues for Clinicians
title_fullStr The Rationale for Monitoring Cognitive Function in Multiple Sclerosis: Practical Issues for Clinicians
title_full_unstemmed The Rationale for Monitoring Cognitive Function in Multiple Sclerosis: Practical Issues for Clinicians
title_short The Rationale for Monitoring Cognitive Function in Multiple Sclerosis: Practical Issues for Clinicians
title_sort rationale for monitoring cognitive function in multiple sclerosis: practical issues for clinicians
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008981/
https://www.ncbi.nlm.nih.gov/pubmed/30008964
http://dx.doi.org/10.2174/1874205X01812010031
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