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Grinspan syndrome with periodontitis: Coincidence or correlation?
Grinspan syndrome is a syndromic complex which comprises a triad of hypertension, diabetes, and oral lichen planus. It remains an enigmatic condition that whether it is separate entity or drug-induced lichenoid reaction emerging due to medications used to treat hypertension and diabetes. Diabetes is...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009158/ https://www.ncbi.nlm.nih.gov/pubmed/29962708 http://dx.doi.org/10.4103/jisp.jisp_142_18 |
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author | Goyal, Lata Gupta, Narinder Dev Gupta, Namita |
author_facet | Goyal, Lata Gupta, Narinder Dev Gupta, Namita |
author_sort | Goyal, Lata |
collection | PubMed |
description | Grinspan syndrome is a syndromic complex which comprises a triad of hypertension, diabetes, and oral lichen planus. It remains an enigmatic condition that whether it is separate entity or drug-induced lichenoid reaction emerging due to medications used to treat hypertension and diabetes. Diabetes is related to long-term hyperglycinemia leading to accelerated destruction of both nonmineralized connective tissue and bone leading to periodontitis. Moreover, there is also a possible link between cardiovascular disease and periodontitis. Here, we are presenting a case with the symptomatic triad fulfilling the diagnostic criteria of Grinspan syndrome. A 50-year-old female with type 2 diabetes mellitus and vascular hypertension came with the chief complaint of bleeding gums and severe burning sensation of the oral cavity. In addition, she was having generalized alveolar bone loss and clinical attachment loss. To the best of our knowledge, this coexistence has not been reported earlier. This needs further evaluation so that the preventive measures can be taken at early stage. |
format | Online Article Text |
id | pubmed-6009158 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-60091582018-06-29 Grinspan syndrome with periodontitis: Coincidence or correlation? Goyal, Lata Gupta, Narinder Dev Gupta, Namita J Indian Soc Periodontol Case Report Grinspan syndrome is a syndromic complex which comprises a triad of hypertension, diabetes, and oral lichen planus. It remains an enigmatic condition that whether it is separate entity or drug-induced lichenoid reaction emerging due to medications used to treat hypertension and diabetes. Diabetes is related to long-term hyperglycinemia leading to accelerated destruction of both nonmineralized connective tissue and bone leading to periodontitis. Moreover, there is also a possible link between cardiovascular disease and periodontitis. Here, we are presenting a case with the symptomatic triad fulfilling the diagnostic criteria of Grinspan syndrome. A 50-year-old female with type 2 diabetes mellitus and vascular hypertension came with the chief complaint of bleeding gums and severe burning sensation of the oral cavity. In addition, she was having generalized alveolar bone loss and clinical attachment loss. To the best of our knowledge, this coexistence has not been reported earlier. This needs further evaluation so that the preventive measures can be taken at early stage. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6009158/ /pubmed/29962708 http://dx.doi.org/10.4103/jisp.jisp_142_18 Text en Copyright: © 2018 Indian Society of Periodontology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Goyal, Lata Gupta, Narinder Dev Gupta, Namita Grinspan syndrome with periodontitis: Coincidence or correlation? |
title | Grinspan syndrome with periodontitis: Coincidence or correlation? |
title_full | Grinspan syndrome with periodontitis: Coincidence or correlation? |
title_fullStr | Grinspan syndrome with periodontitis: Coincidence or correlation? |
title_full_unstemmed | Grinspan syndrome with periodontitis: Coincidence or correlation? |
title_short | Grinspan syndrome with periodontitis: Coincidence or correlation? |
title_sort | grinspan syndrome with periodontitis: coincidence or correlation? |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009158/ https://www.ncbi.nlm.nih.gov/pubmed/29962708 http://dx.doi.org/10.4103/jisp.jisp_142_18 |
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