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Grinspan syndrome with periodontitis: Coincidence or correlation?

Grinspan syndrome is a syndromic complex which comprises a triad of hypertension, diabetes, and oral lichen planus. It remains an enigmatic condition that whether it is separate entity or drug-induced lichenoid reaction emerging due to medications used to treat hypertension and diabetes. Diabetes is...

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Autores principales: Goyal, Lata, Gupta, Narinder Dev, Gupta, Namita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009158/
https://www.ncbi.nlm.nih.gov/pubmed/29962708
http://dx.doi.org/10.4103/jisp.jisp_142_18
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author Goyal, Lata
Gupta, Narinder Dev
Gupta, Namita
author_facet Goyal, Lata
Gupta, Narinder Dev
Gupta, Namita
author_sort Goyal, Lata
collection PubMed
description Grinspan syndrome is a syndromic complex which comprises a triad of hypertension, diabetes, and oral lichen planus. It remains an enigmatic condition that whether it is separate entity or drug-induced lichenoid reaction emerging due to medications used to treat hypertension and diabetes. Diabetes is related to long-term hyperglycinemia leading to accelerated destruction of both nonmineralized connective tissue and bone leading to periodontitis. Moreover, there is also a possible link between cardiovascular disease and periodontitis. Here, we are presenting a case with the symptomatic triad fulfilling the diagnostic criteria of Grinspan syndrome. A 50-year-old female with type 2 diabetes mellitus and vascular hypertension came with the chief complaint of bleeding gums and severe burning sensation of the oral cavity. In addition, she was having generalized alveolar bone loss and clinical attachment loss. To the best of our knowledge, this coexistence has not been reported earlier. This needs further evaluation so that the preventive measures can be taken at early stage.
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spelling pubmed-60091582018-06-29 Grinspan syndrome with periodontitis: Coincidence or correlation? Goyal, Lata Gupta, Narinder Dev Gupta, Namita J Indian Soc Periodontol Case Report Grinspan syndrome is a syndromic complex which comprises a triad of hypertension, diabetes, and oral lichen planus. It remains an enigmatic condition that whether it is separate entity or drug-induced lichenoid reaction emerging due to medications used to treat hypertension and diabetes. Diabetes is related to long-term hyperglycinemia leading to accelerated destruction of both nonmineralized connective tissue and bone leading to periodontitis. Moreover, there is also a possible link between cardiovascular disease and periodontitis. Here, we are presenting a case with the symptomatic triad fulfilling the diagnostic criteria of Grinspan syndrome. A 50-year-old female with type 2 diabetes mellitus and vascular hypertension came with the chief complaint of bleeding gums and severe burning sensation of the oral cavity. In addition, she was having generalized alveolar bone loss and clinical attachment loss. To the best of our knowledge, this coexistence has not been reported earlier. This needs further evaluation so that the preventive measures can be taken at early stage. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6009158/ /pubmed/29962708 http://dx.doi.org/10.4103/jisp.jisp_142_18 Text en Copyright: © 2018 Indian Society of Periodontology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Goyal, Lata
Gupta, Narinder Dev
Gupta, Namita
Grinspan syndrome with periodontitis: Coincidence or correlation?
title Grinspan syndrome with periodontitis: Coincidence or correlation?
title_full Grinspan syndrome with periodontitis: Coincidence or correlation?
title_fullStr Grinspan syndrome with periodontitis: Coincidence or correlation?
title_full_unstemmed Grinspan syndrome with periodontitis: Coincidence or correlation?
title_short Grinspan syndrome with periodontitis: Coincidence or correlation?
title_sort grinspan syndrome with periodontitis: coincidence or correlation?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009158/
https://www.ncbi.nlm.nih.gov/pubmed/29962708
http://dx.doi.org/10.4103/jisp.jisp_142_18
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