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Cross-coupling of dissimilar ketone enolates via enolonium species to afford non-symmetrical 1,4-diketones
Due to their closely matched reactivity, the coupling of two dissimilar ketone enolates to form a 1,4-diketone remains a challenge in organic synthesis. We herein report that umpolung of a ketone trimethylsilyl enol ether (1 equiv) to form a discrete enolonium species, followed by addition of as lit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009205/ https://www.ncbi.nlm.nih.gov/pubmed/29977370 http://dx.doi.org/10.3762/bjoc.14.84 |