Formation of Neural Precursor Cell Populations by Differentiation of Embryonic Stem Cells In Vitro

Recent interest in the generation of neural lineages by differentiation of embryonic stem cells arises from the opportunities represented by a developmentally normal, unlimited source of material that can be manipulated genetically with precision. Several experimental approaches, which differ concep...

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Detalles Bibliográficos
Autores principales: Rathjen, Joy, Rathjen, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2002
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009522/
https://www.ncbi.nlm.nih.gov/pubmed/12805994
http://dx.doi.org/10.1100/tsw.2002.134
Descripción
Sumario:Recent interest in the generation of neural lineages by differentiation of embryonic stem cells arises from the opportunities represented by a developmentally normal, unlimited source of material that can be manipulated genetically with precision. Several experimental approaches, which differ conceptually, in the route of differentiation and the characteristics of the resulting cell population have been reported. In this review we undertake a comparative analysis of these approaches and their suitability for experimental investigation or implantation.

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