A novel long non-coding RNA from NBL2 pericentromeric macrosatellite forms a perinucleolar aggregate structure in colon cancer

Primate-specific NBL2 macrosatellite is hypomethylated in several types of tumors, yet the consequences of this DNA hypomethylation remain unknown. We show that NBL2 conserved repeats are close to the centromeres of most acrocentric chromosomes. NBL2 associates with the perinucleolar region and unde...

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Detalles Bibliográficos
Autores principales: Dumbović, Gabrijela, Biayna, Josep, Banús, Jordi, Samuelsson, Johanna, Roth, Anna, Diederichs, Sven, Alonso, Sergio, Buschbeck, Marcus, Perucho, Manuel, Forcales, Sonia-V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009586/
https://www.ncbi.nlm.nih.gov/pubmed/29912433
http://dx.doi.org/10.1093/nar/gky263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009586/
https://www.ncbi.nlm.nih.gov/pubmed/29912433
http://dx.doi.org/10.1093/nar/gky263

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