Cell penetrating thiazole peptides inhibit c-MYC expression via site-specific targeting of c-MYC G-quadruplex

The structural differences among different G-quadruplexes provide an opportunity for site-specific targeting of a particular G-quadruplex structure. However, majority of G-quadruplex ligands described thus far show little selectivity among different G-quadruplexes. In this work, we delineate the des...

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Detalles Bibliográficos
Autores principales: Dutta, Debasish, Debnath, Manish, Müller, Diana, Paul, Rakesh, Das, Tania, Bessi, Irene, Schwalbe, Harald, Dash, Jyotirmayee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009605/
https://www.ncbi.nlm.nih.gov/pubmed/29762718
http://dx.doi.org/10.1093/nar/gky385

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