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Na(+)/Ca(2+) Exchanger a Druggable Target to Promote β-Cell Proliferation and Function

An important feature of type 2 diabetes is a decrease in β-cell mass. Therefore, it is essential to find new approaches to stimulate β-cell proliferation. We have previously shown that heterozygous inactivation of the Na(+)/Ca(2+) exchanger (isoform 1; NCX1), a protein responsible for Ca(2+) extrusi...

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Detalles Bibliográficos
Autores principales:	Papin, Julien, Zummo, Francesco Paolo, Pachera, Nathalie, Guay, Claudiane, Regazzi, Romano, Cardozo, Alessandra K, Herchuelz, André
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009611/ https://www.ncbi.nlm.nih.gov/pubmed/29942927 http://dx.doi.org/10.1210/js.2017-00370

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