The KDM4A/KDM4C/NF-κB and WDR5 epigenetic cascade regulates the activation of B cells

T follicular helper (Tfh) cell-derived signals promote activation and proliferation of antigen-primed B cells. It remains unclear whether epigenetic regulation is involved in the B cell responses to Tfh cell-derived signals. Here, we demonstrate that Tfh cell-mimicking signals induce the expression...

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Detalles Bibliográficos
Autores principales: Hung, Kuo-Hsuan, Woo, Yong H, Lin, I-Ying, Liu, Chin-Hsiu, Wang, Li-Chieh, Chen, Hsin-Yu, Chiang, Bor-Luen, Lin, Kuo-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009645/
https://www.ncbi.nlm.nih.gov/pubmed/29718303
http://dx.doi.org/10.1093/nar/gky281

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