StpA and Hha stimulate pausing by RNA polymerase by promoting DNA–DNA bridging of H-NS filaments

In enterobacteria, AT-rich horizontally acquired genes, including virulence genes, are silenced through the actions of at least three nucleoid-associated proteins (NAPs): H-NS, StpA and Hha. These proteins form gene-silencing nucleoprotein filaments through direct DNA binding by H-NS and StpA homodi...

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Detalles Bibliográficos
Autores principales: Boudreau, Beth A, Hron, Daniel R, Qin, Liang, van der Valk, Ramon A, Kotlajich, Matthew V, Dame, Remus T, Landick, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009659/
https://www.ncbi.nlm.nih.gov/pubmed/29718386
http://dx.doi.org/10.1093/nar/gky265

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