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The TREX2 3′→ 5′ Exonuclease Physically Interacts with DNA Polymerase δ and Increases Its Accuracy

Proofreading function by the 3′→ 5′ exonuclease of DNA polymerase δ (pol δ) is consistent with the observation that deficiency of the associated exonuclease can lead to a strong mutation phenotype, high error rates during DNA replication, and ultimately cancer. We have isolated pol δ(d) from isotoni...

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Detalles Bibliográficos
Autores principales: Shevelev, Igor V., Ramadan, Kristijan, Hubscher, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009725/
https://www.ncbi.nlm.nih.gov/pubmed/12806015
http://dx.doi.org/10.1100/tsw.2002.99