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Organic Solute Transporter α-β Protects Ileal Enterocytes From Bile Acid–Induced Injury

BACKGROUND & AIMS: Ileal bile acid absorption is mediated by uptake via the apical sodium-dependent bile acid transporter (ASBT), and export via the basolateral heteromeric organic solute transporter α-β (OSTα-OSTβ). In this study, we investigated the cytotoxic effects of enterocyte bile acid st...

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Detalles Bibliográficos
Autores principales: Ferrebee, Courtney B., Li, Jianing, Haywood, Jamie, Pachura, Kimberly, Robinson, Brian S., Hinrichs, Benjamin H., Jones, Rheinallt M., Rao, Anuradha, Dawson, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009794/
https://www.ncbi.nlm.nih.gov/pubmed/29930976
http://dx.doi.org/10.1016/j.jcmgh.2018.01.006