New quinoxalinone inhibitors targeting secreted phospholipase A2 and α-glucosidase

Elevated blood glucose and increased activities of secreted phospholipase A2 (sPLA2) are strongly linked to coronary heart disease. In this report, our goal was to develop small heterocyclic compound that inhibit sPLA2. The title compounds were also tested against α-glucosidase and α-amylase. This a...

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Detalles Bibliográficos
Autores principales: Alasmary, Fatmah A. S., Alnahdi, Fatima S., Ben Bacha, Abir, El-Araby, Amr M., Moubayed, Nadine, Alafeefy, Ahmed M., El-Araby, Moustafa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009887/
https://www.ncbi.nlm.nih.gov/pubmed/28856929
http://dx.doi.org/10.1080/14756366.2017.1363743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009887/
https://www.ncbi.nlm.nih.gov/pubmed/28856929
http://dx.doi.org/10.1080/14756366.2017.1363743

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