Anticancer evaluation and molecular modeling of multi-targeted kinase inhibitors based pyrido[2,3-d]pyrimidine scaffold

An efficient synthesis of substituted pyrido[2,3-d]pyrimidines was carried out and evaluated for in vitro anticancer activity against five cancer cell lines, namely hepatic cancer (HepG-2), prostate cancer (PC-3), colon cancer (HCT-116), breast cancer (MCF-7), and lung cancer (A-549) cell lines. Reg...

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Detalles Bibliográficos
Autores principales: Elzahabi, Heba S. A., Nossier, Eman S., Khalifa, Nagy M., Alasfoury, Rania A., El-Manawaty, May A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009920/
https://www.ncbi.nlm.nih.gov/pubmed/29482389
http://dx.doi.org/10.1080/14756366.2018.1437729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009920/
https://www.ncbi.nlm.nih.gov/pubmed/29482389
http://dx.doi.org/10.1080/14756366.2018.1437729

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