Pentabromopseudilin: a myosin V inhibitor suppresses TGF-β activity by recruiting the type II TGF-β receptor to lysosomal degradation

Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour, and phytotoxic activities. In mammalian cells, PBrP is known to act as a reversible and allosteric inhibitor of myosin...

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Detalles Bibliográficos
Autores principales: Shih-Wei, Wang, Chih-Ling, Chung, Kao, Yu-Chen, Martin, René, Knölker, Hans-Joachim, Shiao, Meng-Shin, Chen, Chun-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009923/
https://www.ncbi.nlm.nih.gov/pubmed/29768059
http://dx.doi.org/10.1080/14756366.2018.1465416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009923/
https://www.ncbi.nlm.nih.gov/pubmed/29768059
http://dx.doi.org/10.1080/14756366.2018.1465416

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