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Synthesis and evaluation of novel spiro derivatives for pyrrolopyrimidines as anti-hyperglycemia promising compounds

Pyrrolopyrimidin-4-ylidene-malononitriles IIa–d were prepared as important intermediates for preparation of a new series of spiro-pyrrolopyrimidines. These intermediates undergo cyclisation via reaction with acetylacetone, guanidine hydrochloride or hydrazine hydrate. Elemental and spectroscopic evi...

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Detalles Bibliográficos
Autores principales:	Fatahala, Samar Said, Mahgub, Shahenda, Taha, Heba, Abd-El Hameed, Rania Helmy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009929/ https://www.ncbi.nlm.nih.gov/pubmed/29708461 http://dx.doi.org/10.1080/14756366.2018.1461854

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