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Bulge oligonucleotide as an inhibitory agent of bacterial topoisomerase I
Bacterial topoisomerase I (Btopo I) was defined as potential target for discovery of new antibacterial compounds. Various oligonucleotides containing bulge structure were designed and synthesised as inhibitors to Btopo I in this investigation. The results of this study demonstrated that the designed...
Autores principales: | Yang, Zhaoqi, Jiang, Tuoyu, Zhong, Hanshi, Kang, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009931/ https://www.ncbi.nlm.nih.gov/pubmed/29281935 http://dx.doi.org/10.1080/14756366.2017.1419218 |
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