Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors

Cannabinoid (CB) and opioid systems are both involved in analgesia, food intake, mood and behavior. Due to the co-localization of µ-opioid (MOR) and CB1 receptors in various regions of the central nervous system (CNS) and their ability to form heterodimers, bivalent ligands targeting to both these s...

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Detalles Bibliográficos
Autores principales: Mollica, Adriano, Pelliccia, Sveva, Famiglini, Valeria, Stefanucci, Azzurra, Macedonio, Giorgia, Chiavaroli, Annalisa, Orlando, Giustino, Brunetti, Luigi, Ferrante, Claudio, Pieretti, Stefano, Novellino, Ettore, Benyhe, Sandor, Zador, Ferenc, Erdei, Anna, Szucs, Edina, Samavati, Reza, Dvorácskó, Szabolcs, Tomboly, Csaba, Ragno, Rino, Patsilinakos, Alexandros, Silvestri, Romano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009935/
https://www.ncbi.nlm.nih.gov/pubmed/28097916
http://dx.doi.org/10.1080/14756366.2016.1260565

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