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Comparing hydrazine-derived reactive groups as inhibitors of quinone-dependent amine oxidases
Lysyl oxidase has emerged as an important enzyme in cancer metastasis. Its activity has been reported to become upregulated in several types of cancer, and blocking its activity has been shown to limit the metastatic potential of various cancers. The small-molecules phenylhydrazine and β-aminopropio...
Autores principales: | Burke, Ashley A., Severson, Elizabeth S., Mool, Shreya, Solares Bucaro, Maria J., Greenaway, Frederick T., Jakobsche, Charles E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009937/ https://www.ncbi.nlm.nih.gov/pubmed/28110559 http://dx.doi.org/10.1080/14756366.2016.1265518 |
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