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Comparing hydrazine-derived reactive groups as inhibitors of quinone-dependent amine oxidases

Lysyl oxidase has emerged as an important enzyme in cancer metastasis. Its activity has been reported to become upregulated in several types of cancer, and blocking its activity has been shown to limit the metastatic potential of various cancers. The small-molecules phenylhydrazine and β-aminopropio...

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Detalles Bibliográficos
Autores principales: Burke, Ashley A., Severson, Elizabeth S., Mool, Shreya, Solares Bucaro, Maria J., Greenaway, Frederick T., Jakobsche, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009937/
https://www.ncbi.nlm.nih.gov/pubmed/28110559
http://dx.doi.org/10.1080/14756366.2016.1265518

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