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Hemodynamic performance within crossed stent grafts: computational and experimental study on the effect of cross position and angle

BACKGROUND AND AIMS: The crossed limbs stent graft technique is regularly employed to treat abdominal aortic aneurysm patients with unfavorable aneurysm necks or widely splayed common iliac arteries. This article numerically evaluates the hemodynamic performance of the crossed limbs strategy by anal...

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Detalles Bibliográficos
Autores principales: Liu, Ming, Sun, Anqiang, Deng, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009958/
https://www.ncbi.nlm.nih.gov/pubmed/29921281
http://dx.doi.org/10.1186/s12938-018-0517-1
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author Liu, Ming
Sun, Anqiang
Deng, Xiaoyan
author_facet Liu, Ming
Sun, Anqiang
Deng, Xiaoyan
author_sort Liu, Ming
collection PubMed
description BACKGROUND AND AIMS: The crossed limbs stent graft technique is regularly employed to treat abdominal aortic aneurysm patients with unfavorable aneurysm necks or widely splayed common iliac arteries. This article numerically evaluates the hemodynamic performance of the crossed limbs strategy by analyzing numerical simulations and conducting experiments using two series of idealized bifurcated stent grafts with different cross angles and cross positions. RESULTS: Results demonstrated that the absolute helicity at outlets decreased with increased cross angles and increased with decreased cross positions. The time-averaged wall shear stress remained approximately unchanged, whereas the oscillating shear index and relative resident time decreased slightly when the cross angle increased and cross position decreased in iliac grafts. Additionally, both numerical and in vitro experimental results indicate the displacement force acting on the stent graft gradually increased as cross angles increased and cross positions decreased. Results further indicated that strip areas with a high oscillating shear index and high relative resident time, which may be vulnerable to thrombosis formation, exist along the outer surface of the iliac artery grafts. CONCLUSION: Given this information, the optimal crossed limbs configuration may contain a small cross angle and low cross position; however, low cross positions may increase the risk of migration.
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spelling pubmed-60099582018-06-27 Hemodynamic performance within crossed stent grafts: computational and experimental study on the effect of cross position and angle Liu, Ming Sun, Anqiang Deng, Xiaoyan Biomed Eng Online Research BACKGROUND AND AIMS: The crossed limbs stent graft technique is regularly employed to treat abdominal aortic aneurysm patients with unfavorable aneurysm necks or widely splayed common iliac arteries. This article numerically evaluates the hemodynamic performance of the crossed limbs strategy by analyzing numerical simulations and conducting experiments using two series of idealized bifurcated stent grafts with different cross angles and cross positions. RESULTS: Results demonstrated that the absolute helicity at outlets decreased with increased cross angles and increased with decreased cross positions. The time-averaged wall shear stress remained approximately unchanged, whereas the oscillating shear index and relative resident time decreased slightly when the cross angle increased and cross position decreased in iliac grafts. Additionally, both numerical and in vitro experimental results indicate the displacement force acting on the stent graft gradually increased as cross angles increased and cross positions decreased. Results further indicated that strip areas with a high oscillating shear index and high relative resident time, which may be vulnerable to thrombosis formation, exist along the outer surface of the iliac artery grafts. CONCLUSION: Given this information, the optimal crossed limbs configuration may contain a small cross angle and low cross position; however, low cross positions may increase the risk of migration. BioMed Central 2018-06-19 /pmc/articles/PMC6009958/ /pubmed/29921281 http://dx.doi.org/10.1186/s12938-018-0517-1 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Liu, Ming
Sun, Anqiang
Deng, Xiaoyan
Hemodynamic performance within crossed stent grafts: computational and experimental study on the effect of cross position and angle
title Hemodynamic performance within crossed stent grafts: computational and experimental study on the effect of cross position and angle
title_full Hemodynamic performance within crossed stent grafts: computational and experimental study on the effect of cross position and angle
title_fullStr Hemodynamic performance within crossed stent grafts: computational and experimental study on the effect of cross position and angle
title_full_unstemmed Hemodynamic performance within crossed stent grafts: computational and experimental study on the effect of cross position and angle
title_short Hemodynamic performance within crossed stent grafts: computational and experimental study on the effect of cross position and angle
title_sort hemodynamic performance within crossed stent grafts: computational and experimental study on the effect of cross position and angle
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009958/
https://www.ncbi.nlm.nih.gov/pubmed/29921281
http://dx.doi.org/10.1186/s12938-018-0517-1
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