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Upregulation of the EMT marker vimentin is associated with poor clinical outcome in acute myeloid leukemia

BACKGROUND: Vimentin (VIM) is a type III intermediate filament that maintains cell integrity, and is involved in cell migration, motility and adhesion. When overexpressed in solid cancers, vimentin drives epithelial to mesenchymal transition (EMT) and ultimately, metastasis. The effects of its overe...

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Detalles Bibliográficos
Autores principales:	Wu, Sharon, Du, Yang, Beckford, John, Alachkar, Houda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009962/ https://www.ncbi.nlm.nih.gov/pubmed/29925392 http://dx.doi.org/10.1186/s12967-018-1539-y

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