Synthesis and biological evaluation of benzenesulphonamide-bearing 1,4,5-trisubstituted-1,2,3-triazoles possessing human carbonic anhydrase I, II, IV, and IX inhibitory activity

A library of benzenesulphonamides incorporating 1,2,3-triazole rings functionalised with ester, carboxylic acid, carboxamide, carboxyhydrazide, and hydroxymethyl moieties were synthesised. The carbonic anhydrase (CAs, EC 4.2.1.1) inhibitory activity of the new compounds was assessed against four hum...

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Detalles Bibliográficos
Autores principales: Kumar, Rajiv, Sharma, Vikas, Bua, Silvia, Supuran, Claudiu T., Sharma, Pawan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009984/
https://www.ncbi.nlm.nih.gov/pubmed/28891338
http://dx.doi.org/10.1080/14756366.2017.1367775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009984/
https://www.ncbi.nlm.nih.gov/pubmed/28891338
http://dx.doi.org/10.1080/14756366.2017.1367775

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