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Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines
4-(3-(4-Substituted-phenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl) benzenesulfonamides (9–16) were successfully synthesized and their chemical structures were confirmed by (1)H NMR, (13)C NMR, and HRMS spectra. Carbonic anhydrase I and II inhibitory effects of the compounds were investigated. K(i) va...
Autores principales: | Gul, Halise Inci, Mete, Ebru, Taslimi, Parham, Gulcin, Ilhami, Supuran, Claudiu T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010057/ https://www.ncbi.nlm.nih.gov/pubmed/27774818 http://dx.doi.org/10.1080/14756366.2016.1244533 |
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