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Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid
Pharmacological interventions targeting mitochondria present several barriers for a complete efficacy. Therefore, a new mitochondriotropic antioxidant (AntiOxBEN(3)) based on the dietary antioxidant gallic acid was developed. AntiOxBEN(3) accumulated several thousand-fold inside isolated rat liver m...
Autores principales: | Teixeira, José, Oliveira, Catarina, Cagide, Fernando, Amorim, Ricardo, Garrido, Jorge, Borges, Fernanda, Oliveira, Paulo J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010063/ https://www.ncbi.nlm.nih.gov/pubmed/29513043 http://dx.doi.org/10.1080/14756366.2018.1442831 |
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