CAIX furthers tumour progression in the hypoxic tumour microenvironment of esophageal carcinoma and is a possible therapeutic target

The hypoxic tumour microenvironment of solid tumours represents an important starting point for modulating progression and metastatic spread. Carbonic anhydrase IX (CAIX) is a known HIF-1α-dependent key player in maintaining cell pH conditions under hypoxia. We show that CAIX is strongly expressed i...

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Detalles Bibliográficos
Autores principales: Drenckhan, Astrid, Freytag, Morton, Supuran, Claudiu T., Sauter, Guido, Izbicki, Jakob R., Gros, Stephanie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010094/
https://www.ncbi.nlm.nih.gov/pubmed/29865880
http://dx.doi.org/10.1080/14756366.2018.1475369

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