Small molecule KDM4s inhibitors as anti-cancer agents

Histone demethylation is a vital process in epigenetic regulation of gene expression. A number of histone demethylases are present to control the methylated states of histone. Among these enzymes, KDM4s are one subfamily of JmjC KDMs and play important roles in both normal and cancer cells. The disc...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Hongzhi, Li, Qihang, Li, Qi, Zhu, Jie, Gu, Kai, Jiang, Xueyang, Hu, Qianqian, Feng, Feng, Qu, Wei, Chen, Yao, Sun, Haopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010108/
https://www.ncbi.nlm.nih.gov/pubmed/29651880
http://dx.doi.org/10.1080/14756366.2018.1455676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010108/
https://www.ncbi.nlm.nih.gov/pubmed/29651880
http://dx.doi.org/10.1080/14756366.2018.1455676

Ejemplares similares