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Cancer stem cells CD133 inhibition and cytotoxicity of certain 3-phenylthiazolo[3,2-a]benzimidazoles: design, direct synthesis, crystal study and in vitro biological evaluation
Cancer stem cells (CSCs) have been objects of intensive study since their identification in 1994. Adopting a structural rigidification approach, a novel series of 3-phenylthiazolo[3,2-a]benzimidazoles 4a–d was designed and synthesised, in an attempt to develop potent anticancer agent that can target...
Autores principales: | Al-Ansary, Ghada H., Eldehna, Wagdy M., Ghabbour, Hazem A., Al-Rashood, Sara T. A., Al-Rashood, Khalid A., Eladwy, Radwa A., Al-Dhfyan, Abdullah, Kabil, Maha M., Abdel-Aziz, Hatem A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010115/ https://www.ncbi.nlm.nih.gov/pubmed/28726519 http://dx.doi.org/10.1080/14756366.2017.1347166 |
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