Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease

Oxalates stimulate alterations in renal epithelial cells and thereby induce calcium oxalate (CaOx) stone formation. Bacillus subtilis YvrK gene encodes for oxalate decarboxylase (OxdC) which degrades oxalate to formate and CO(2). The present work is aimed to clone the oxdC gene in a mammalian expres...

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Detalles Bibliográficos
Autores principales: Albert, Abhishek, Tiwari, Vidhi, Paul, Eldho, Ganesan, Divya, Ayyavu, Mahesh, Kujur, Ritu, Ponnusamy, Sasikumar, Shanmugam, Kathiresan, Saso, Luciano, Govindan Sadasivam, Selvam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010120/
https://www.ncbi.nlm.nih.gov/pubmed/28118755
http://dx.doi.org/10.1080/14756366.2016.1256884

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