Synthesis, in vitro antitumour activity, and molecular docking study of novel 2-substituted mercapto-3-(3,4,5-trimethoxybenzyl)-4(3H)-quinazolinone analogues

A novel series of 2-substituted mercapto-3-(3,4,5-trimethoxybenzyl)-4(3H)-quinazolinones 1–20 was synthesised and evaluated for in vitro antitumour activity. N-(4-Chlorophenyl)-2-[(3-(3,4,5-trimethoxybenzyl)-4(3H)-quinazolinon-2-yl)thio)acetamide (7) and N-(3,4,5 trimethoxybenzyl)-2-[(3-(3,4,5-trime...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Azab, Adel S., Abdel-Aziz, Alaa A.-M., Ghabbour, Hazem A., Al-Gendy, Manal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010141/
https://www.ncbi.nlm.nih.gov/pubmed/28948843
http://dx.doi.org/10.1080/14756366.2017.1368504

Ejemplares similares

Ejemplares similares