Biochemical characterisation of a Kunitz-type inhibitor from Tamarindus indica L. seeds and its efficacy in reducing plasma leptin in an experimental model of obesity

A trypsin inhibitor isolated from tamarind seed (TTI) has satietogenic effects in animals, increasing the cholecystokinin (CCK) in eutrophy and reducing leptin in obesity. We purified TTI (pTTI), characterised, and observed its effect upon CCK and leptin in obese Wistar rats. By HPLC, and after ampl...

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Detalles Bibliográficos
Autores principales: de Medeiros, Amanda Fernandes, Costa, Izael de Sousa, de Carvalho, Fabiana Maria Coimbra, Kiyota, Sumika, de Souza, Beatriz Blenda Pinheiro, Sifuentes, Daniel Nogoceke, Serquiz, Raphael Paschoal, Maciel, Bruna Leal Lima, Uchôa, Adriana Ferreira, dos Santos, Elizeu Antunes, Morais, Ana Heloneida de Araújo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010142/
https://www.ncbi.nlm.nih.gov/pubmed/29322840
http://dx.doi.org/10.1080/14756366.2017.1419220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010142/
https://www.ncbi.nlm.nih.gov/pubmed/29322840
http://dx.doi.org/10.1080/14756366.2017.1419220

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