dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments

Recent single-cell RNA-seq protocols based on droplet microfluidics use massively multiplexed barcoding to enable simultaneous measurements of transcriptomes for thousands of individual cells. The increasing complexity of such data creates challenges for subsequent computational processing and troub...

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Detalles Bibliográficos
Autores principales: Petukhov, Viktor, Guo, Jimin, Baryawno, Ninib, Severe, Nicolas, Scadden, David T., Samsonova, Maria G., Kharchenko, Peter V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010209/
https://www.ncbi.nlm.nih.gov/pubmed/29921301
http://dx.doi.org/10.1186/s13059-018-1449-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010209/
https://www.ncbi.nlm.nih.gov/pubmed/29921301
http://dx.doi.org/10.1186/s13059-018-1449-6

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