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dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments
Recent single-cell RNA-seq protocols based on droplet microfluidics use massively multiplexed barcoding to enable simultaneous measurements of transcriptomes for thousands of individual cells. The increasing complexity of such data creates challenges for subsequent computational processing and troub...
Autores principales: | Petukhov, Viktor, Guo, Jimin, Baryawno, Ninib, Severe, Nicolas, Scadden, David T., Samsonova, Maria G., Kharchenko, Peter V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010209/ https://www.ncbi.nlm.nih.gov/pubmed/29921301 http://dx.doi.org/10.1186/s13059-018-1449-6 |
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