Cargando…

Escherichia coli β-clamp slows down DNA polymerase I dependent nick translation while accelerating ligation

The nick translation property of DNA polymerase I (Pol I) ensures the maturation of Okazaki fragments by removing primer RNAs and facilitating ligation. However, prolonged nick translation traversing downstream DNA is an energy wasting futile process, as Pol I simultaneously polymerizes and depolyme...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhardwaj, Amit, Ghose, Debarghya, Thakur, Krishan Gopal, Dutta, Dipak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010275/ https://www.ncbi.nlm.nih.gov/pubmed/29924849 http://dx.doi.org/10.1371/journal.pone.0199559

Ejemplares similares

MGME1 processes flaps into ligatable nicks in concert with DNA polymerase γ during mtDNA replication
por: Uhler, Jay P., et al.
Publicado: (2016)

Unchecked nick ligation can promote localized genome re-replication
por: Johansson, Erik, et al.
Publicado: (2021)

Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA
por: Zheng, Fengwei, et al.
Publicado: (2020)

A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA
por: Liu, Xingchen, et al.
Publicado: (2022)

Free spermidine evokes superoxide radicals that manifest toxicity
por: Kumar, Vineet, et al.
Publicado: (2022)

Exchange between Escherichia coli polymerases II and III on a processivity clamp
por: Kath, James E., et al.
Publicado: (2016)

Exo1 protects DNA nicks from ligation to promote crossover formation during meiosis
por: Gioia, Michael, et al.
Publicado: (2023)

Clamping down on mismatches
por: Li, Guo-Min
Publicado: (2016)

Nick Adams
por: Hemingway, Ernest, 1899-1961
Publicado: (1974)

In the nick of time
por: Leslie, Mitch
Publicado: (2001)

“Nick Nax”
Publicado: (1859)

Engineering nicking enzymes that preferentially nick 5-methylcytosine-modified DNA
por: Gutjahr, Alice, et al.
Publicado: (2014)

Structure-Guided Designing and Evaluation of Peptides Targeting Bacterial Transcription
por: Kaur, Gundeep, et al.
Publicado: (2020)

Nick Charles, detective (The thin man) /
por: Hammett, Dashiell, 1894-1961
Publicado: (1944)

RNA-guided DNA base damage repair via DNA polymerase-mediated nick translation
por: Tsegay, Pawlos S, et al.
Publicado: (2022)

Collision with duplex DNA renders Escherichia coli DNA polymerase III holoenzyme susceptible to DNA polymerase IV-mediated polymerase switching on the sliding clamp
por: Le, Thanh Thi, et al.
Publicado: (2017)

CLAMPing down on microtubules in migratory cells
por: Leslie, Mitch
Publicado: (2014)

Antibodies clamp down on NET nucleosomes
por: Radic, Marko
Publicado: (2020)

Implications of Metastable Nicks and Nicked Holliday Junctions in Processing Joint Molecules in Mitosis and Meiosis
por: Machín, Félix
Publicado: (2020)

The ring-type polymerase sliding clamp family
por: Bruck, Irina, et al.
Publicado: (2001)

Slow unloading leads to DNA-bound β(2)-sliding clamp accumulation in live Escherichia coli cells
por: Moolman, M. Charl, et al.
Publicado: (2014)

Zika: information in the nick of time
por: Walker, Jessica L, et al.
Publicado: (2017)

Labeling of unique sequences in double-stranded DNA at sites of vicinal nicks generated by nicking endonucleases
por: Kuhn, Heiko, et al.
Publicado: (2008)

GEN1 promotes Holliday junction resolution by a coordinated nick and counter-nick mechanism
por: Chan, Ying Wai, et al.
Publicado: (2015)

Solution study of the Escherichia coli DNA polymerase III clamp loader reveals the location of the dynamic ψχ heterodimer
por: Tondnevis, Farzaneh, et al.
Publicado: (2015)

The Escherichia coli clamp loader rapidly remodels SSB on DNA to load clamps
por: Newcomb, Elijah S P, et al.
Publicado: (2022)

R-loops and nicks initiate DNA breakage and genome instability in non-growing Escherichia coli
por: Wimberly, Hallie, et al.
Publicado: (2013)

RNA ligation of very small pseudo nick structures by T4 RNA ligase 2, leading to efficient production of versatile RNA rings
por: Cheng, Kai, et al.
Publicado: (2019)

Essays on the future: in honor of Nick Metropolis
por: Hecker, Siegfried, et al.
Publicado: (2000)

Initiation of homologous recombination at DNA nicks
por: Maizels, Nancy, et al.
Publicado: (2018)

Contributions of the individual hydrophobic clefts of the Escherichia coli β sliding clamp to clamp loading, DNA replication and clamp recycling
por: Scouten Ponticelli, Sarah K., et al.
Publicado: (2009)

The Escherichia coli Clamp Loader Can Actively Pry Open the β-Sliding Clamp
por: Paschall, Christopher O., et al.
Publicado: (2011)

Corrigendum: R-loops and nicks initiate DNA breakage and genome instability in non-growing Escherichia coli
por: Wimberly, Hallie, et al.
Publicado: (2014)

Kinetic mechanism and fidelity of nick sealing by Escherichia coli NAD(+)-dependent DNA ligase (LigA)
por: Chauleau, Mathieu, et al.
Publicado: (2016)

Slowing the body slows down time perception
por: De Kock, Rose, et al.
Publicado: (2021)

To Nick or Not to Nick: Comparison of I-SceI Single- and Double-Strand Break-Induced Recombination in Yeast and Human Cells
por: Katz, Samantha S., et al.
Publicado: (2014)

Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks
por: Vriend, Lianne E.M., et al.
Publicado: (2016)

Nick Lane: Unearthing the first cellular innovations
por: Powell, Kendall
Publicado: (2015)

First person – Gigi Lau and Nick Barts
Publicado: (2019)

Pathways and signatures of mutagenesis at targeted DNA nicks
por: Zhang, Yinbo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bsus5ak062mtcsc9la9th4e69n