Cargando…

Exenatide ameliorates hepatic steatosis and attenuates fat mass and FTO gene expression through PI3K signaling pathway in nonalcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is a common disease associated with metabolic syndrome and can lead to life-threatening complications like hepatic carcinoma and cirrhosis. Exenatide, a glucagon-like peptide-1 (GLP-1) receptor agonist antidiabetic drug, has the capacity to overcome insulin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Shan, Wang, Xiaoman, Zhang, Jielei, Li, Jingyi, Liu, Xiaogang, Ma, Yuanyuan, Han, Chao, Zhang, Lixia, Zheng, Lili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Associação Brasileira de Divulgação Científica 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010322/ https://www.ncbi.nlm.nih.gov/pubmed/29924135 http://dx.doi.org/10.1590/1414-431X20187299

Ejemplares similares

Fat mass and obesity–associated protein promotes liver steatosis by targeting PPARα
por: Wei, Xiaohui, et al.
Publicado: (2022)

Sulforaphane Attenuates Nonalcoholic Fatty Liver Disease by Inhibiting Hepatic Steatosis and Apoptosis
por: Li, Jinwang, et al.
Publicado: (2021)

Fermented ginseng, GBCK25, ameliorates steatosis and inflammation in nonalcoholic steatohepatitis model
por: Choi, Naeun, et al.
Publicado: (2019)

Prolyl endopeptidase gene disruption attenuates high fat diet-induced nonalcoholic fatty liver disease in mice by improving hepatic steatosis and inflammation
por: Jiang, Dai-Xi, et al.
Publicado: (2020)

Obeticholic acid ameliorates obesity and hepatic steatosis by activating brown fat
por: Zhang, Hanlin, et al.
Publicado: (2021)

Lactobacillus attenuates progression of nonalcoholic fatty liver disease by lowering cholesterol and steatosis
por: Lee, Na Young, et al.
Publicado: (2021)

Toyocamycin attenuates free fatty acid-induced hepatic steatosis and apoptosis in cultured hepatocytes and ameliorates nonalcoholic fatty liver disease in mice
por: Takahara, Ikuko, et al.
Publicado: (2017)

Exenatide with Metformin Ameliorated Visceral Adiposity and Insulin Resistance
por: Du, Xuan, et al.
Publicado: (2018)

Correction: Toyocamycin attenuates free fatty acid-induced hepatic steatosis and apoptosis in cultured hepatocytes and ameliorates nonalcoholic fatty liver disease in mice
por: Takahara, Ikuko, et al.
Publicado: (2020)

Nrf2 deletion causes “benign” simple steatosis to develop into nonalcoholic steatohepatitis in mice fed a high-fat diet
por: Wang, Chunhua, et al.
Publicado: (2013)

Exenatide and dapagliflozin combination improves markers of liver steatosis and fibrosis in patients with type 2 diabetes
por: Gastaldelli, Amalia, et al.
Publicado: (2019)

Fructus Xanthii Attenuates Hepatic Steatosis in Rats Fed on High-Fat Diet
por: Li, Xiumin, et al.
Publicado: (2013)

Andrographolide ameliorates hepatic steatosis by suppressing FATP2-mediated fatty acid uptake in mice with nonalcoholic fatty liver disease
por: Ran, Li-Sha, et al.
Publicado: (2022)

Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis
por: Porteiro, Begoña, et al.
Publicado: (2017)

Quinoa Ameliorates Hepatic Steatosis, Oxidative Stress, Inflammation and Regulates the Gut Microbiota in Nonalcoholic Fatty Liver Disease Rats
por: Zhong, Lingyue, et al.
Publicado: (2023)

Exenatide induces carcinoembryonic antigen‐related cell adhesion molecule 1 expression to prevent hepatic steatosis
por: Ghadieh, Hilda E., et al.
Publicado: (2017)

Upregulation of adiponectin by Ginsenoside Rb1 contributes to amelioration of hepatic steatosis induced by high fat diet
por: Li, Yaru, et al.
Publicado: (2022)

Does Nonalcoholic Pancreatic Steatosis Always Correlate with Nonalcoholic Fatty Liver Disease?
por: Ulasoglu, Celal, et al.
Publicado: (2021)

Silencing of FABP1 ameliorates hepatic steatosis, inflammation, and oxidative stress in mice with nonalcoholic fatty liver disease
por: Mukai, Takako, et al.
Publicado: (2017)

The GLP-1 Receptor Agonist Exenatide Ameliorates Bone Composition and Tissue Material Properties in High Fat Fed Diabetic Mice
por: Mansur, Sity Aishah, et al.
Publicado: (2019)

Effect of FTO Expression and Polymorphism on Fat Deposition in Suzhong Pigs
por: Fu, Yanfeng, et al.
Publicado: (2013)

l-Fucose ameliorates high-fat diet-induced obesity and hepatic steatosis in mice
por: Wu, Guangyan, et al.
Publicado: (2018)

Prebiotic Xylo-Oligosaccharides Ameliorate High-Fat-Diet-Induced Hepatic Steatosis in Rats
por: Lensu, Sanna, et al.
Publicado: (2020)

Hepatocyte-specific PKCβ deficiency protects against high-fat diet-induced nonalcoholic hepatic steatosis
por: Shu, Yaoling, et al.
Publicado: (2020)

Angelica sinensis Suppresses Body Weight Gain and Alters Expression of the FTO Gene in High-Fat-Diet Induced Obese Mice
por: Zhong, Tao, et al.
Publicado: (2017)

Isorhamnetin Alleviates Steatosis and Fibrosis in Mice with Nonalcoholic Steatohepatitis
por: Ganbold, Munkhzul, et al.
Publicado: (2019)

Downregulation of Fat Mass and Obesity Associated (FTO) Promotes the Progression of Intrahepatic Cholangiocarcinoma
por: Rong, Zhuo-Xian, et al.
Publicado: (2019)

Relationship between Controlled Attenuation Parameter and Hepatic Steatosis as Assessed by Ultrasound in Alcoholic or Nonalcoholic Fatty Liver Disease
por: Ahn, Jem Ma, et al.
Publicado: (2016)

Farnesoid X receptor agonist INT-767 attenuates liver steatosis and inflammation in rat model of nonalcoholic steatohepatitis
por: Hu, Ying-Bin, et al.
Publicado: (2018)

Inhibition of Plasminogen Activator Inhibitor 1 Attenuates Hepatic Steatosis but Does Not Prevent Progressive Nonalcoholic Steatohepatitis in Mice
por: Henkel, Anne S., et al.
Publicado: (2018)

Exenatide Attenuates Non-Alcoholic Steatohepatitis by Inhibiting the Pyroptosis Signaling Pathway
por: Liu, Yu, et al.
Publicado: (2021)

Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients
por: Zeybel, Mujdat, et al.
Publicado: (2021)

Exenatide inhibits NF-κB and attenuates ER stress in diabetic cardiomyocyte models
por: Fu, Zhenhong, et al.
Publicado: (2020)

MicroRNA-451 and Genistein Ameliorate Nonalcoholic Steatohepatitis in Mice
por: Gan, Mailin, et al.
Publicado: (2019)

Catalpol induces autophagy and attenuates liver steatosis in ob/ob and high-fat diet-induced obese mice
por: Ren, Huihui, et al.
Publicado: (2019)

Correction to: l-Fucose ameliorates high-fat diet-induced obesity and hepatic steatosis in mice
por: Wu, Guangyan, et al.
Publicado: (2020)

Exenatide Protects Against Cardiac Dysfunction by Attenuating Oxidative Stress in the Diabetic Mouse Heart
por: Ding, Wei, et al.
Publicado: (2019)

(Pro)Renin Receptor Antagonism Attenuates High-Fat-Diet–Induced Hepatic Steatosis
por: Gayban, Ariana Julia B., et al.
Publicado: (2023)

Effect of skin–capsular distance on controlled attenuation parameter for diagnosing liver steatosis in patients with nonalcoholic fatty liver disease
por: Kimura, Syunichiro, et al.
Publicado: (2021)

IκBζ regulates the development of nonalcoholic fatty liver disease through the attenuation of hepatic steatosis in mice
por: Ishikawa, Hideki, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t6qif1anrcaform3vbuct6r9aj