SET-9 and SET-26 are H3K4me3 readers and play critical roles in germline development and longevity

C. elegans SET-9 and SET-26 are highly homologous paralogs that share redundant functions in germline development, but SET-26 alone plays a key role in longevity and heat stress response. Whereas SET-26 is broadly expressed, SET-9 is only detectable in the germline, which likely accounts for their d...

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Detalles Bibliográficos
Autores principales: Wang, Wenke, Chaturbedi, Amaresh, Wang, Minghui, An, Serim, Santhi Velayudhan, Satheeja, Lee, Siu Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010342/
https://www.ncbi.nlm.nih.gov/pubmed/29714684
http://dx.doi.org/10.7554/eLife.34970

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