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ERK1/2 and p38 regulate inter-individual variability in ozone-mediated IL-8 gene expression in primary human bronchial epithelial cells

Inter-individual variability is observed in all biological responses; however this variability is difficult to model and its underlying mechanisms are often poorly understood. This issue currently impedes understanding the health effects of the air pollutant ozone. Ozone produces pulmonary inflammat...

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Detalles Bibliográficos
Autores principales: Bowers, Emma C., McCullough, Shaun D., Morgan, David S., Dailey, Lisa A., Diaz-Sanchez, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010411/
https://www.ncbi.nlm.nih.gov/pubmed/29925859
http://dx.doi.org/10.1038/s41598-018-27662-0