High throughput screening of mitochondrial bioenergetics in human differentiated myotubes identifies novel enhancers of muscle performance in aged mice

Mitochondrial dysfunction is increasingly recognized as a contributor to age-related muscle loss and functional impairment. Therefore, we developed a high throughput screening strategy that enabled the identification of compounds boosting mitochondrial energy production in a human skeletal muscle ce...

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Detalles Bibliográficos
Autores principales: Biesemann, Nadine, Ried, Janina S., Ding-Pfennigdorff, Danping, Dietrich, Axel, Rudolph, Christine, Hahn, Steffen, Hennerici, Wolfgang, Asbrand, Christian, Leeuw, Thomas, Strübing, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010423/
https://www.ncbi.nlm.nih.gov/pubmed/29925868
http://dx.doi.org/10.1038/s41598-018-27614-8

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