Enhanced proliferation of pancreatic acinar cells in MRL/MpJ mice is driven by severe acinar injury but independent of inflammation

Adult pancreatic acinar cells have the ability to re-enter the cell cycle and proliferate upon injury or tissue loss. Despite this mitotic ability, the extent of acinar proliferation is often limited and unable to completely regenerate the injured tissue or restore the initial volume of the organ, t...

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Detalles Bibliográficos
Autores principales: Bombardo, Marta, Malagola, Ermanno, Chen, Rong, Carta, Arcangelo, Seleznik, Gitta M., Hills, Andrew P., Graf, Rolf, Sonda, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010442/
https://www.ncbi.nlm.nih.gov/pubmed/29925922
http://dx.doi.org/10.1038/s41598-018-27422-0

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