Intraamniotic Zika virus inoculation of pregnant rhesus macaques produces fetal neurologic disease

Zika virus (ZIKV) infection of pregnant women can cause fetal microcephaly and other neurologic defects. We describe the development of a non-human primate model to better understand fetal pathogenesis. To reliably induce fetal infection at defined times, four pregnant rhesus macaques are inoculated...

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Detalles Bibliográficos
Autores principales: Coffey, Lark L., Keesler, Rebekah I., Pesavento, Patricia A., Woolard, Kevin, Singapuri, Anil, Watanabe, Jennifer, Cruzen, Christina, Christe, Kari L., Usachenko, Jodie, Yee, JoAnn, Heng, Victoria A., Bliss-Moreau, Eliza, Reader, J. Rachel, von Morgenland, Wilhelm, Gibbons, Anne M., Jackson, Kenneth, Ardeshir, Amir, Heimsath, Holly, Permar, Sallie, Senthamaraikannan, Paranthaman, Presicce, Pietro, Kallapur, Suhas G., Linnen, Jeffrey M., Gao, Kui, Orr, Robert, MacGill, Tracy, McClure, Michelle, McFarland, Richard, Morrison, John H., Van Rompay, Koen K. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010452/
https://www.ncbi.nlm.nih.gov/pubmed/29925843
http://dx.doi.org/10.1038/s41467-018-04777-6

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