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Shift from stochastic to spatially-ordered expression of serine-glycine synthesis enzymes in 3D microtumors
Cell-to-cell differences in protein expression in normal tissues and tumors are a common phenomenon, but the underlying principles that govern this heterogeneity are largely unknown. Here, we show that in monolayer cancer cell-line cultures, the expression of the five metabolic enzymes of serine-gly...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010463/ https://www.ncbi.nlm.nih.gov/pubmed/29925909 http://dx.doi.org/10.1038/s41598-018-27266-8 |