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Transforming Growth Factor-β and Interleukin-10 Synergistically Regulate Humoral Immunity via Modulating Metabolic Signals
Inhibitory cytokines, such as transforming growth factor-β (TGF-β) and interleukin-10 (IL-10), are humoral factors involved in the suppressive function of regulatory T cells and play critical roles in maintaining immune homeostasis. However, TGF-β and IL-10 also have pleiotropic effects and induce h...
Autores principales: | Komai, Toshihiko, Inoue, Mariko, Okamura, Tomohisa, Morita, Kaoru, Iwasaki, Yukiko, Sumitomo, Shuji, Shoda, Hirofumi, Yamamoto, Kazuhiko, Fujio, Keishi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010538/ https://www.ncbi.nlm.nih.gov/pubmed/29963056 http://dx.doi.org/10.3389/fimmu.2018.01364 |
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