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APOE and Alzheimer’s Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction

Apolipoprotein E4 (ApoE4) is the strongest genetic risk factor for late onset Alzheimer’s Disease (AD), and is associated with impairments in cerebral metabolism and cerebrovascular function. A substantial body of literature now points to E4 as a driver of multiple impairments seen in AD, including...

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Detalles Bibliográficos
Autores principales:	Brandon, Jason A., Farmer, Brandon C., Williams, Holden C., Johnson, Lance A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010552/ https://www.ncbi.nlm.nih.gov/pubmed/29962946 http://dx.doi.org/10.3389/fnagi.2018.00180

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