Cargando…
Thick Filament Mechano-Sensing in Skeletal and Cardiac Muscles: A Common Mechanism Able to Adapt the Energetic Cost of the Contraction to the Task
A dual regulation of contraction operates in both skeletal and cardiac muscles. The first mechanism, based on Ca(2+)-dependent structural changes of the regulatory proteins in the thin filament, makes the actin sites available for binding of the myosin motors. The second recruits the myosin heads fr...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010558/ https://www.ncbi.nlm.nih.gov/pubmed/29962967 http://dx.doi.org/10.3389/fphys.2018.00736 |