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Thick Filament Mechano-Sensing in Skeletal and Cardiac Muscles: A Common Mechanism Able to Adapt the Energetic Cost of the Contraction to the Task
A dual regulation of contraction operates in both skeletal and cardiac muscles. The first mechanism, based on Ca(2+)-dependent structural changes of the regulatory proteins in the thin filament, makes the actin sites available for binding of the myosin motors. The second recruits the myosin heads fr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010558/ https://www.ncbi.nlm.nih.gov/pubmed/29962967 http://dx.doi.org/10.3389/fphys.2018.00736 |