miR‐1‐3p and miR‐206 sensitizes HGF‐induced gefitinib‐resistant human lung cancer cells through inhibition of c‐Met signalling and EMT

Hepatocyte growth factor (HGF) overexpression is an important mechanism in acquired epidermal growth factor receptor (EGFR) kinase inhibitor gefitinib resistance in lung cancers with EGFR activating mutations. MiR‐1‐3p and miR‐206 act as suppressors in lung cancer proliferation and metastasis. Howev...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiao, Demin, Chen, Jun, Li, Yu, Tang, Xiali, Wang, Jian, Xu, Wei, Song, Jia, Li, You, Tao, Huimin, Chen, Qingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010770/
https://www.ncbi.nlm.nih.gov/pubmed/29664235
http://dx.doi.org/10.1111/jcmm.13629

Ejemplares similares

Ejemplares similares